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Immune responses to Epstein–Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity

Rowe, Martin and Zuo, Jianmin (2010) Immune responses to Epstein–Barr virus: molecular interactions in the virus evasion of CD8+ T cell immunity. Microbes and Infection, 12 (3). p. 173. ISSN 12864579

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URL of Published Version: http://dx.doi.org/10.1016/j.micinf.2009.12.001

Identification Number/DOI: doi:10.1016/j.micinf.2009.12.001

Persistent viruses have mechanisms for modulating the host immune responses that are essential for achieving a lifelong virus–host balance while minimizing the viral pathogenicity. Here we review some of the immune-modulating mechanisms evolved by the ubiquitous but potentially oncogenic Epstein–Barr virus, with particular emphasis on the molecular mechanisms of genes interfering with HLA class I antigen presentation

Type of Work:Article
Date:2010 (Publication)
School/Faculty:Colleges (2008 onwards) > College of Medical & Dental Sciences
Department:Cancer Studies
Subjects:R Medicine (General)
Institution:University of Birmingham
Copyright Holders:Elsevier Masson SAS
ID Code:309
Refereed:YES
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